Become a Member of our Team!

Scientist I/II, Functional Genomics

Who Are We?

We are on a mission to help patients regain independence through the thoughtful design of safe and reversible therapeutics. You may be, accurately, wondering “how do you do this”? Well, our team is developing a proprietary technology platform to target various regenerative pathways critical for the establishment of complex diseases.

We are looking for team members to join ASAP.

Our small but rapidly growing team currently operates out of South San Francisco. We are easily accessible from SF, the Peninsula, and the East Bay (for those interested in the occasional ferry rides).

Responsibilities

  • Develop the high-throughput screening for a portfolio of cell therapy applications

  • Develop DNA constructs and CRISPR libraries

  • Develops, evaluates, optimizes and implements new technologies, laboratory protocols, and methodologies for biochemical and cell-based assays

  • Provide expert support for multiplexing and scaling biological readouts across our broader scientific team

  • Maintain familiarity with the relevant current literature and its application to multiplexing readouts and cell therapy

  • Coordinate tasks across multiple projects, demonstrating prioritization and planning

  • Interpret and effectively execute experiments in line with project timelines and goals

Qualifications

  • PhD in molecular biology, biotechnology, pharmaceutical, stem cell or related fields, with 2+ years of relevant research experience in industry or academia

  • Experience with high-throughput functional CRISPR screening; prior experience using gene editing, RNAi, CRISPRa/i, or CRISPR KO strategies

  • Working knowledge of NGS technologies and workflows

  • Ability to quickly learn new skills and knowledge on the job, demonstrate productivity, and deliver high-quality results

  • Exceptional candidates will also possess the following skills:

  • Experience in cellular reprogramming, adult stem cell such as HSCs, MSCs or SSCs culture

  • Familiarity with R or similar environments for pipelining of routine data analysis

  • Collaborative experience with computational biologists and/or software engineers to help develop and use novel tools for construct design, experimental planning and/or data analysis

  • Experience with multiplexing/barcoding approaches for scaling experimental throughput

Epic Bio is an early-stage biotechnology company developing a novel technology platform that can provide safe and persistent control of targeted gene regulation. Our proprietary platform represents an entirely new class of therapeutics that can be leveraged to treat severe disease across numerous therapeutic areas, including complex diseases impacted by multiple genes.

Please contact recruiting@epic-bio.com if interested.